Karenitecin
3 definitions

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A drug being studied in the treatment of cancer. It is a type of topoisomerase inhibitor. It is related to the anticancer drug camptothecin.

FK Reading Ease
47.1

FK Grade Level
High School
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  • This definition has not yet been approved by a moderator.

    A synthetic silicon-containing agent related to camptothecin with antineoplastic properties. Cositecan stabilizes the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks and consequently triggering apoptosis. Because it is lipophilic, karenitecin exhibits enhanced tissue penetration and bio-availability compared to water-soluble camptothecins.

    FK Reading Ease
    -25.7

    FK Grade Level
    Graduate School
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  • A drug being studied in the treatment of cancer. It belongs to a family of drugs called topoisomerase inhibitors. It is related to the anticancer drug camptothecin.

    FK Reading Ease
    44.2

    FK Grade Level
    High School
  • Flag