A drug used to treat Hodgkin lymphoma and malignant melanoma. It is also being studied in the treatment of other types of cancer. Dacarbazine attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent.
A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.