CCLB8
2 definitions

CCLB8

A chimeric (made from human and mouse proteins) monoclonal antibody being studied in the treatment of advanced kidney cancer and other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. cCLB8 works by blocking inflammation and tumor growth. Also called anti-IL-6 chimeric monoclonal antibody and CNTO 328.

CCLB8

A drug used to treat a rare condition called Castleman disease in patients who do not have HIV or human herpesvirus 8. It is also being studied in the treatment of multiple myeloma. CCLB8 binds to a protein called interleukin-6 (IL-6), which is made by some white blood cells and other cells in the body. CCLB8 may help reduce inflammation and stop the growth of cancer cells or abnormal blood cells. It is a type of monoclonal antibody.

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About this term

CCLB8 has been defined 2 different ways in documents like Glossary of Cancer Terms, NCI Dictionary of Cancer Terms.

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