An antibody produced by a single B cell or its identical progeny that is specific for a given antigen. Monoclonal antibodies are used as research tools for binding to specific protein molecules and are invaluable in research, medicine, and industry.
The smallest amount of a specific chemical substance. Large molecules such as proteins, fats, carbohydrates, and nucleic acids are the building blocks of a cell, and a gene determines how each molecule is produced.
A subset of T cells and B cells that have been exposed to antigens and can then respond more readily when the immune system encounters those same antigens again.
A granulocyte found in tissue. The contents of mast cells, along with those of basophils, are responsible for the symptoms of allergy.
A group of genes that controls several aspects of the immune response. MHC genes code for “self” markers on all body cells.
A large and versatile immune cell that devours invading pathogens and other intruders. Macrophages stimulate other immune cells by presenting them with small pieces of the invaders.
Powerful chemical substances secreted by lymphocytes. These molecules help direct and regulate the immune responses.
An organ of the immune system where lymphocytes develop and congregate. These organs include the bone marrow, thymus, lymph nodes, spleen, and various other clusters of lymphoid tissue. Blood vessels and lymphatic vessels are also lymphoid organs.
A small white blood cell produced in the lymphoid organs and essential to immune defenses. B cells, T cells, and NK T cells are lymphocytes.
A bodywide network of channels, similar to the blood vessels, which transports lymph to the immune organs and into the bloodstream.